Predictors and potentiators of psychedelic-occasioned mystical experiences

Abstract Mystical experiences are often described as being among the most profound and meaningful events of a person’s life. Their occurrence, while normal but uncommon phenomenon, is reliably occasioned by psychedelic substances under appropriate conditions, although care needed around context usage to help ensure safe beneficial experiences. The occurrence mystical in sessions key mediator sustained psychological benefits reported both healthy clinical populations. Certain factors including set setting, drug dosage, trait absorption, type, intention states surrender acceptance all predict or influence Various additional may further contribute intensity enhance their long-term benefits, music, meditation spiritual practices nature-based settings. This review examines these considers how they might be optimised increase chances experience occurring, also considering that negatively associated with suggestions on mitigated where applicable. Finally, potential future research avenues for furthering our knowledge enhanced suggested. Maximising an important aspect application psychedelics.